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Klotho Wellness

The Systems Health Analysis

A written model of your biology, not a list of numbers.

Every analysis is assembled with AI from two decades of systems medicine practice. A physician reviews it, and your clinician refines it against what they heard from you.

Nine systems

Assessed individually, then connected.

  1. 01Metabolic & glycemic
  2. 02Cardiovascular & lipid
  3. 03Endocrine & hormonal
  4. 04Immune & inflammatory
  5. 05Detoxification & hepatic
  6. 06Renal & electrolyte
  7. 07Hematologic & iron
  8. 08Neurocognitive
  9. 09Nutrient & mitochondrial

What the document contains

A cross-system interaction map

How inflammation is shaping your lipids. How your cortisol curve is shaping your blood sugar. Software that reads one marker at a time can't see this. It's the reason a systems physician exists.

Root causes, ranked

Your three to five highest-leverage changes, in order of expected effect, instead of forty flagged values. Most people have already been given the list. Nobody has given them the order.

A specific, sequenced protocol

Nutrition, lifestyle and targeted supplementation, dosed and sequenced. Precision and Signature members also get prescriptions, peptide therapies and bioregulators, managed by your clinician.

Whole-person inputs, not just serum

Your cognitive testing, Quality of Life Inventory and Health & Lifestyle Assessment are read alongside your blood work. Cognition, environment and meaning are physiology too.

A twelve-month trajectory

What should change by your follow-up panel, by how much, and what it means if it doesn't. Your next labs arrive with a hypothesis already attached.

What we measure

135+ unique biomarkers. Every one used.

Panel size isn’t the point. Depth in the right places is. We built this panel backward from the analysis, so every marker answers a question the systems model needs answered.

How we count, and why it matters

A lab test is not a biomarker. A comprehensive metabolic panel is one test that reports close to twenty biomarkers. And a “biomarker count” in this industry often adds up repeat measurements: a platform can re-run the same markers mid-year and count them twice.

We report the numbers separately. Your annual panel is 41 lab tests reporting 135+ unique biomarkers, each counted once. With your follow-up panel, Precision adds up to 220+ biomarker measurements a year (300+ on Signature). Ask any program you are comparing us to for the same numbers.

Beyond blood

  • Health & Lifestyle Assessment

    History, symptoms, lifestyle, stressors and life satisfaction: the context your labs cannot give.

  • CNS Vital Signs

    Computerized neurocognitive testing that objectively measures brain performance across domains.

  • Quality of Life Inventory

    A validated measure of how satisfied you are across the areas of life that matter to you.

Platinum Lab Panel

Your annual panel, drawn once at a patient service center near you. 41 lab tests reporting 135+ unique biomarkers across every system the analysis models. Reflex tests are added where clinically indicated.

Metabolic & glycemic

  • Comprehensive metabolic panel
  • Hemoglobin A1c with estimated average glucose
  • Fasting insulin
  • Fructosamine
  • Uric acid
  • Adiponectin
  • Leptin

Cardiovascular & lipid

  • NMR LipoProfile with lipids and insulin-resistance score
  • Apolipoprotein A1, B and ratio
  • Lipoprotein(a)
  • High-sensitivity cardiac CRP
  • Fibrinogen activity
  • Homocysteine

Endocrine & hormonal

  • Testosterone, free and total
  • Estradiol
  • Progesterone
  • DHEA-sulfate
  • Sex hormone binding globulin
  • FSH and LH
  • Morning cortisol

Thyroid

  • TSH, free T4, free T3 and reverse T3
  • Thyroid peroxidase and thyroglobulin antibodies

Immune & autoimmune

  • ANA by IFA, with reflex to titer and pattern
  • Rheumatoid factor

Hematologic & iron

  • CBC with differential and platelets
  • Ferritin
  • Iron and TIBC
  • Transferrin

Nutrient & mitochondrial

  • Fatty acid balance, including omega-3 index
  • Vitamin D, 25-hydroxy
  • Vitamin B12 and folate
  • Methylmalonic acid
  • RBC magnesium
  • RBC zinc
  • Copper

Renal, hepatic & digestive

  • Complete urinalysis
  • Cystatin C
  • GGT
  • Amylase
  • Lipase

Screening

  • Prostate-specific antigen (men)

Follow-up panel

16 tests reporting 85 biomarkers, included once with Precision and twice with Signature. Every marker here responds to your protocol. The panel answers one question, whether the plan is working, and comes back as an updated Systems Health Analysis.

Core chemistry & hematology

  • Comprehensive metabolic panel
  • CBC with differential and platelets
  • Complete urinalysis
  • GGT

Metabolic response

  • Hemoglobin A1c with estimated average glucose
  • Fasting insulin
  • Fructosamine
  • Uric acid

Cardiovascular response

  • NMR LipoProfile with lipids
  • Apolipoprotein B
  • High-sensitivity cardiac CRP
  • Homocysteine

Nutrient repletion

  • Vitamin D, 25-hydroxy
  • Vitamin B12 and folate
  • RBC magnesium
  • RBC zinc

Stop collecting data. Start reading the system.

Every program starts with a free consult: a short call about your goals and whether Klotho is the right fit. No cost, no commitment.

Just have a question? Email info@klothowellness.com or call 512-522-0966.